Search results for: an-introduction-to-mathematical-epidemiology

An Introduction to Mathematical Epidemiology

Author : Maia Martcheva
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The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases. It includes model building, fitting to data, local and global analysis techniques. Various types of deterministic dynamical models are considered: ordinary differential equation models, delay-differential equation models, difference equation models, age-structured PDE models and diffusion models. It includes various techniques for the computation of the basic reproduction number as well as approaches to the epidemiological interpretation of the reproduction number. MATLAB code is included to facilitate the data fitting and the simulation with age-structured models.

An Introduction to Mathematical Modeling of Infectious Diseases

Author : Michael Y. Li
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This text provides essential modeling skills and methodology for the study of infectious diseases through a one-semester modeling course or directed individual studies. The book includes mathematical descriptions of epidemiological concepts, and uses classic epidemic models to introduce different mathematical methods in model analysis. Matlab codes are also included for numerical implementations. It is primarily written for upper undergraduate and beginning graduate students in mathematical sciences who have an interest in mathematical modeling of infectious diseases. Although written in a rigorous mathematical manner, the style is not unfriendly to non-mathematicians.

Mathematical Epidemiology

Author : Fred Brauer
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Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (

An Introduction to Mathematical Physiology and Biology

Author : J. Mazumdar
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A textbook about the mathematical modelling of biological and physiological phenomena for mathematically sophisticated students.

Mathematical Models in Population Biology and Epidemiology

Author : Fred Brauer
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The goal of this book is to search for a balance between simple and analyzable models and unsolvable models which are capable of addressing important questions on population biology. Part I focusses on single species simple models including those which have been used to predict the growth of human and animal population in the past. Single population models are, in some sense, the building blocks of more realistic models -- the subject of Part II. Their role is fundamental to the study of ecological and demographic processes including the role of population structure and spatial heterogeneity -- the subject of Part III. This book, which will include both examples and exercises, is of use to practitioners, graduate students, and scientists working in the field.

A Historical Introduction to Mathematical Modeling of Infectious Diseases

Author : Ivo M. Foppa
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A Historical Introduction to Mathematical Modeling of Infectious Diseases: Seminal Papers in Epidemiology offers step-by-step help on how to navigate the important historical papers on the subject, beginning in the 18th century. The book carefully, and critically, guides the reader through seminal writings that helped revolutionize the field. With pointed questions, prompts, and analysis, this book helps the non-mathematician develop their own perspective, relying purely on a basic knowledge of algebra, calculus, and statistics. By learning from the important moments in the field, from its conception to the 21st century, it enables readers to mature into competent practitioners of epidemiologic modeling. Presents a refreshing and in-depth look at key historical works of mathematical epidemiology Provides all the basic knowledge of mathematics readers need in order to understand the fundamentals of mathematical modeling of infectious diseases Includes questions, prompts, and answers to help apply historical solutions to modern day problems

Mathematical Models in Epidemiology

Author : Fred Brauer
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The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of disease transmission models. It includes (i) an introduction to the main concepts of compartmental models including models with heterogeneous mixing of individuals and models for vector-transmitted diseases, (ii) a detailed analysis of models for important specific diseases, including tuberculosis, HIV/AIDS, influenza, Ebola virus disease, malaria, dengue fever and the Zika virus, (iii) an introduction to more advanced mathematical topics, including age structure, spatial structure, and mobility, and (iv) some challenges and opportunities for the future. There are exercises of varying degrees of difficulty, and projects leading to new research directions. For the benefit of public health professionals whose contact with mathematics may not be recent, there is an appendix covering the necessary mathematical background. There are indications which sections require a strong mathematical background so that the book can be useful for both mathematical modelers and public health professionals.

Mathematical Approaches for Emerging and Reemerging Infectious Diseases An Introduction

Author : Carlos Castillo-Chavez
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This book covers tutorial and research contributions on the use of dynamical systems and stochastic models in disease dynamics. Beginning graduate students in applied mathematics, scientists, or mathematicians who want to enter the fields of mathematical and theoretical epidemiology will find this book useful.

An Introduction to Undergraduate Research in Computational and Mathematical Biology

Author : Hannah Callender Highlander
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Speaking directly to the growing importance of research experience in undergraduate mathematics programs, this volume offers suggestions for undergraduate-appropriate research projects in mathematical and computational biology for students and their faculty mentors. The aim of each chapter is twofold: for faculty, to alleviate the challenges of identifying accessible topics and advising students through the research process; for students, to provide sufficient background, additional references, and context to excite students in these areas and to enable them to successfully undertake these problems in their research. Some of the topics discussed include: • Oscillatory behaviors present in real-world applications, from seasonal outbreaks of childhood diseases to action potentials in neurons • Simulating bacterial growth, competition, and resistance with agent-based models and laboratory experiments • Network structure and the dynamics of biological systems • Using neural networks to identify bird species from birdsong samples • Modeling fluid flow induced by the motion of pulmonary cilia Aimed at undergraduate mathematics faculty and advanced undergraduate students, this unique guide will be a valuable resource for generating fruitful research collaborations between students and faculty.

Mathematical Reviews

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Introduction to Mathematical Oncology

Author : Yang Kuang
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Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

Proceedings of the Berkeley Symposium on Mathematical Statistics and Probability

Author : Jerzy Neyman
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Modeling Paradigms and Analysis of Disease Transmission Models

Author : Abba B. Gumel
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This volume stems from two DIMACS activities, the U.S.-Africa Advanced Study Institute and the DIMACS Workshop, both on Mathematical Modeling of Infectious Diseases in Africa, held in South Africa in the summer of 2007. It contains both tutorial papers and research papers. Students and researchers should find the papers on modeling and analyzing certain diseases currently affecting Africa very informative. In particular, they can learn basic principles of disease modeling and stability from the tutorial papers where continuous and discrete time models, optimal control, and stochastic features are introduced.

Mathematics in Population Biology

Author : Horst R. Thieme
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U S Environmental Protection Agency Library System Book Catalog

Author : United States. Environmental Protection Agency. Library Systems Branch
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Includes the monographic collection of the 28 libraries comprising the Library System of the Environmental Protection Agency.

Mathematical Problems in Biology

Author : P. van den Driessche
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A conference on "Some Mathematical Problems in Biology" was held at the University of Victoria, Victoria, B. C. , Canada, from May 7 - 10, 1973. The participants and invited speakers were mathematicians interested in problems of a biological nature, and scientists actively engaged in developing mathematical models in biological fields. One aim of the conference was to attempt to assess what the recent rapid growth of mathematical interaction with the biosciences has accomplished and may accomplish in the near future. The conference also aimed to expose the problems of communication bet~",een mathematicians and biological scientists, and in doing so to stimulate the interchange of ideas. It was recognised that the topic spans an enormous breadth, and little attempt was made to balance the very diverse areas. Widespread active interest was shown in the conference, and just over one hundred people registered. The varied departments and institutions across North America from which the participants came made it both academically and geographically mixed. The chief activity of the conference was the presentation of papers. Nine invited guest speakers (see table of contents) each gave a one hour talk. These covered a wide range of topics. There were twenty-five shorter (twenty minute) contributed papers, and almost all papers l,rere followed by a five minute question and discussion period. Duplicated abstracts of presented papers were available at the meeting. An evening informal discussion meeting of participants, chaired by Dr. A. B. Tayler, and led by Drs. E. M. Hagmeier, E. C.

The Geographic Spread of Infectious Diseases

Author : Lisa Sattenspiel
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The 1918-19 influenza epidemic killed more than fifty million people worldwide. The SARS epidemic of 2002-3, by comparison, killed fewer than a thousand. The success in containing the spread of SARS was due largely to the rapid global response of public health authorities, which was aided by insights resulting from mathematical models. Models enabled authorities to better understand how the disease spread and to assess the relative effectiveness of different control strategies. In this book, Lisa Sattenspiel and Alun Lloyd provide a comprehensive introduction to mathematical models in epidemiology and show how they can be used to predict and control the geographic spread of major infectious diseases. Key concepts in infectious disease modeling are explained, readers are guided from simple mathematical models to more complex ones, and the strengths and weaknesses of these models are explored. The book highlights the breadth of techniques available to modelers today, such as population-based and individual-based models, and covers specific applications as well. Sattenspiel and Lloyd examine the powerful mathematical models that health authorities have developed to understand the spatial distribution and geographic spread of influenza, measles, foot-and-mouth disease, and SARS. Analytic methods geographers use to study human infectious diseases and the dynamics of epidemics are also discussed. A must-read for students, researchers, and practitioners, no other book provides such an accessible introduction to this exciting and fast-evolving field.

Dynamical Systems and Their Applications in Biology

Author : Shigui Ruan
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This volume is based on the proceedings of the International Workshop on Dynamical Systems and their Applications in Biology held at the Canadian Coast Guard College on Cape Breton Island (Nova Scotia, Canada). It presents a broad picture of the current research surrounding applications of dynamical systems in biology, particularly in population biology. The book contains 19 papers and includes articles on the qualitative and/or numerical analysis of models involving ordinary, partial, functional, and stochastic differential equations. Applications include epidemiology, population dynamics, and physiology. The material is suitable for graduate students and research mathematicians interested in ordinary differential equations and their applications in biology. Also available by Ruan, Wolkowicz, and Wu is Differential Equations with Applications to Biology, Volume 21 in the AMS series Fields Institute Communications.

Mathematical and Statistical Estimation Approaches in Epidemiology

Author : Gerardo Chowell
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Mathematical and Statistical Estimation Approaches in Epidemiology compiles t- oretical and practical contributions of experts in the analysis of infectious disease epidemics in a single volume. Recent collections have focused in the analyses and simulation of deterministic and stochastic models whose aim is to identify and rank epidemiological and social mechanisms responsible for disease transmission. The contributions in this volume focus on the connections between models and disease data with emphasis on the application of mathematical and statistical approaches that quantify model and data uncertainty. The book is aimed at public health experts, applied mathematicians and sci- tists in the life and social sciences, particularly graduate or advanced undergraduate students, who are interested not only in building and connecting models to data but also in applying and developing methods that quantify uncertainty in the context of infectious diseases. Chowell and Brauer open this volume with an overview of the classical disease transmission models of Kermack-McKendrick including extensions that account for increased levels of epidemiological heterogeneity. Their theoretical tour is followed by the introduction of a simple methodology for the estimation of, the basic reproduction number,R . The use of this methodology 0 is illustrated, using regional data for 1918–1919 and 1968 in uenza pandemics.

Bio Mathematics

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