Search results for: asymmetric-cell-division

Asymmetric Cell Division

Author : Alvaro Macieira-Coelho
File Size : 85.37 MB
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Cell biologists have recently come to understand that asymmetry of division is an important regulatory phenomenon in the fate of a cell. In adult organisms asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to aging. This book describes the phenomenon in different organisms and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.

Asymmetric Cell Division in Development Differentiation and Cancer

Author : Jean-Pierre Tassan
File Size : 32.96 MB
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This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.

The Mechanisms of Spindle Positioning in Asymmetric Cell Divisions of the Early C Elegans Embryo

Author : Meng-Fu Bryan Tsou
File Size : 55.45 MB
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Asymmetric Cell Divisions and Cell Fate Specification in C Elegans Neural Development

Author : Aakanksha Singhvi
File Size : 60.83 MB
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Cell Lineage Cell Polarity and Asymmetric Cell Division in the Primary Neurogenic Lineage in the Leech Helobdella Robusta

Author : Shaobing Zhang
File Size : 29.51 MB
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The Cell Cycle and Development

Author : Gregory R. Bock
File Size : 59.35 MB
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This book brings together scientists working at the interface between the cell cycle, cell growth and development in a variety of model systems and research paradigms. The focus is on understanding how such diverse developmental inputs can modulate cell cycle regulation and, reciprocally, how a common way of regulating cell cycle progression can participate in different developmental strategies.

Asymmetric Cell Division in Development Differentiation and Cancer

Author : Jean-Pierre Tassan
File Size : 43.17 MB
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This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.

Miranda Localization During Asymmetric Cell Division of Neuroblasts in Drosophila Melanogaster

Author : Veronika Erben
File Size : 63.84 MB
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Stem Cells From Basic Research to Therapy

Author : Federico Calegari
File Size : 87.5 MB
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The first volume of Stem Cells deals with the fundamental principles that govern embryonic and somatic stem cell biology. Historically, the identification and characterization of such pathways and general rules of stemness occurred during embryonic development and Volume I reflects this with topics spanning cell cycle regulation, epigenetics, and asymmetric cell division in a number of organ systems from planarian to human. Three specific sections discuss i) Basic Stem Cell Biology, ii) Tissue Formation During Development, and iii) Model Organisms with particular emphasis on those more relevant for biomedical research and, thus, leading to the topics addressed in Volume II.

Asymmetric Cell Division in Drosophila melanogaster Neuroblasts

Author : Diana Langer
File Size : 60.58 MB
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Asymmetric cell divisions generate cell diversity. Drosophila neuroblasts divide in an asymmetric manner to generate another neuroblast and a differentiating ganglion mother cell. The adaptor protein Miranda plays a crucial role in creating intrinsic differences in the two daughter cells by asymmetrically localizing key differentiation factors. This thesis describes the identification of potential new components of Miranda complexes. The performed experiments provide a starting point for further investigations on the role of the versatile and multifunctional Miranda protein in Drosophila melanogaster development.