Search results for: peptides-in-energy-balance-and-obesity

Peptides in Energy Balance and Obesity

Author : G. Ühbeck
File Size : 76.27 MB
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Obesity is one of the relevant public health concerns and it is evident that body weight control is achieved through highly integrated physiological interactions like nutrient selection. Presenting an account of the roles of specific peptides in energy balance, this title provides an understanding of the patho-physiology of energy balance.

Advances in Proinsulin Research and Application 2012 Edition

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Advances in Proinsulin Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Proinsulin. The editors have built Advances in Proinsulin Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Proinsulin in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Proinsulin Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Handbook of Biologically Active Peptides

Author : Abba Kastin
File Size : 33.98 MB
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Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. Presents all aspects of biologically active peptides in one resource Features more than 20 sections spanning plant, bacterial, fungal, venom, and invertebrate peptides to general peptides Includes immunological, inflammatory, cancer, vaccine, and neurotrophic peptides Discusses peptide precursors, mRNA distribution, processing, and receptors, not just pathophysiological implications

Adipocytokines Energy Balance and Cancer

Author : Ofer Reizes
File Size : 78.83 MB
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Adipocytokines provide the circuitry by which adipose tissue communicates among its component cells which include adipocytes, stromal cells, immune cells and vascular elements, with adipose tissue depots in other locations throughout the body and with other tissues in order to regulate physiologic processes of energy intake, utilization, and distribution. Since disturbances, both qualitative and quantitative, in adipocytokine function contribute significantly to many of the comorbidities associated with obesity, including diabetes, cardiovascular disease and cancer, this volume, which discusses most of the major adipocytokines independently and collectively and their roles in normal and pathologic processes, should be useful to all individuals seeking a deeper understanding of these processes. Moreover, it provides a valuable complement to the series on Energy Balance and Cancer, in which each volume is focused on a specific aspect of this process, which now constitutes an expanding problem as the obesity pandemic continues and more of the population reaches the age where cancer is most prevalent. This volume should provide a valuable resource to all clinicians and scientists engaged in caring for susceptible patients and in exploring the relation between energy balance and cancer as well as an important platform to providing the background for research development.

The Impact of Obesity and Nutrition on Chronic Liver Diseases An Issue of Clinics in Liver Disease E Book

Author : Zobair Younossi
File Size : 80.86 MB
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Internationally renowned experts present topics related to obesity, nutrition, and liver disease in this issue. In the first article, the epidemiology of obesity and its association with liver disease are covered. The following two articles focus on the roles that visceral adipose tissue and microbiota potentially play in the pathogenesis of obesity-related liver disease. The next article focuses on the hepatic pathology seen in patients with obesity-related liver disease and those with malnutrition. The next five articles are focused on NAFLD and provide in-depth data on the natural history and treatment strategies for patients with NAFLD. The next six articles deal with the impact of obesity on other liver diseases and on special populations including children and liver-transplant recipients. The final article provides the most updated information regarding genomics and genetic targets that may provide better prognostic and diagnostic biomarkers and more personalized treatment targets for patients with NAFLD. Cutting-edge information in this issue will help readers gain better understanding of the natural history and pathogenesis of primary and secondary liver diseases associated with obesity. As the information about obesity-related liver disease expands, clinicians will be able to provide more targeted therapeutic options for these patients and develop more accurate diagnostic and prognostic biomarkers.

Obesity and Metabolism

Author : Márta Korbonits
File Size : 78.73 MB
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It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.

Endocrinology Adult and Pediatric Diabetes Mellitus and Obesity E Book

Author : Gordon C Weir
File Size : 83.63 MB
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Meet the growing challenges of diabetes and obesity management with Endocrinology: Adult and Pediatric: Diabetes Mellitus and Obesity - a new diabetes and obesity eBook from the same expert endocrinologists responsible for the highly acclaimed two-volume Endocrinology clinical reference. With all of the latest advances loaded on your favorite eReader, you’ll be able to put today’s best practices to work for your patients. Stay abreast of the newest knowledge and advances in diabetes mellitus and obesity, including today’s increased focus on controlling autoimmunity and preserving or replenishing beta-cell mass in the management of type 1 diabetes; complications of diabetes and their pathogenesis, morbidity, and treatment; new findings and treatments for obesity; and much more. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and DeGroot, the go-to clinical reference for endocrinologists worldwide. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.

Peptide Drug Discovery and Development

Author : Miguel Castanho
File Size : 30.55 MB
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Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from diverse therapeutic fields, and the lessons to be learned from them, while the final part looks at new targets and opportunities, discussing several drug targets and diseases for which peptide drugs are currently being developed.

Bariatric and Metabolic Surgery An Issue of Surgical Clinics E Book

Author : Shanu Kothari
File Size : 41.88 MB
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A comprehensive review of bariatric and metabolic surgery for the general surgery! Topics include: The obesity epidemic/economic impact and diabetes epidemic/economic impact, physiology of obesity/diabetes, physiology of weight loss surgery, history of bariatric surgery, laparoscopic adjustable gastric banding, sleeve gastrectomy, biliopancreatic diversion/duodenal switch, laparoscopic gastric bypass, complications of laparoscopic adjustable gastric binding, complications of laparoscopic gastric bypass, outcomes/comparative effectiveness studies, co-morbidity reduction data, economic impact of bariatric surgery, adolescent bariatric surgery, revisional bariatric surgery, the future of bariatric surgery, and more!

Peptide Transport and Delivery Into the Central Nervous System

Author : Laszlo Prokai
File Size : 85.43 MB
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Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics could be useful in the treatment of diseases of the central nervous system. This book provides an overview of the role and neuropharmaceutical potential of these peptides, and discusses the state of the art and future trends in the use of peptide pharmacotherapy involving the brain.

Endocrinology Adult and Pediatric E Book

Author : J. Larry Jameson
File Size : 54.38 MB
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Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Consult this title on your favorite e-reader.

Endocrinology E Book

Author : J. Larry Jameson
File Size : 69.56 MB
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ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. This reference is optimally designed to help you succeed in your demanding practice and ensure the best possible outcomes for every patient. Overcome virtually any clinical challenge with detailed, expert coverage of every area of endocrinology, authored by hundreds of leading luminaries in the field. Provide state-of-the-art care with comprehensive updates on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors ... brand-new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis ... expanded coverage of sports performance, including testosterone, androgen research, and bone growth and deterioration ... and the newest discoveries in genetics and how they affect patient care. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information more quickly, while still getting the complete coverage you expect.

Gastroenterologic Issues in the Obese Patient An Issue of Gastroenterology Clinics E Book

Author : David A. Johnson
File Size : 79.19 MB
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Given the prevalence of obesity, any physician providing clinical care will be involved in the care of obese patients. Gastroenterologists will play an active role in the evaluation and treatment of these patients. Thereby, it is essential to fully understand the scope of the problem and the opportunities for intervention. The expert authors assembled for this issue offer expanded insight which can enhance care plans provided to this patient population. Since Dr. Johnson’s first issue published, there are several updates in this area, and the articles in this volume address those. These updates are seen in the areas of medical therapy, surgical options, and endoscopic treatments for obese patients.

Essentials of Cardiopulmonary Physical Therapy E Book

Author : Ellen Hillegass
File Size : 24.78 MB
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Based on best practices prescribed in The Guide to Physical Therapist Practice, Essentials of Cardiopulmonary Physical Therapy, 3rd Edition provides comprehensive coverage of anatomy and physiology, assessment, and aspects of the cardiopulmonary systems, with a focus on their interaction. The disablement model is used in describing the eight cardiopulmonary practice patterns. Expert author Ellen Hillegass also discusses pathophysiology, pharmacology, and interventions in the outpatient setting. Incorporating Guide language, her practical approach progresses logically from basic sciences through intervention, and emphasizes lifespan considerations. Material follows The Guide to Physical Therapist Practice 2nd Edition, reflecting best practices as defined by the American Physical Therapy Association. Evidence-based content is based on the latest research in the field. Case studies show the application of concepts with real-world examples. Pharmacology chapters reflect both the rehabilitation background of physical therapists and the pharmaceutical expertise of a pharmacist. A focus on wellness follows the disablement model. Information on geriatric and pediatric cardiopulmonary physical therapy is easy to apply to patient situations. Testing for both cardiac and pulmonary dysfunction is conveniently located in a single chapter. Cardiovascular medication information covers the latest drugs used in cardiopulmonary physical therapy. Information on thoracic organ transplantation simplifies and explains these complex procedures. NEW chapters cover the lymphatic system and pediatrics. Revised chapters on cardiopulmonary anatomy and physiology differentiate between information that is need to know and that is nice to know. An Evolve companion website includes medical animations to illustrate concepts, along with a glossary, glossary exercises, and reference lists from the book linked to MEDLINE abstracts.

Energy Balance and Obesity in Man

Author : J. S. Garrow
File Size : 84.54 MB
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Obesity

Author : James M. Rippe
File Size : 70.34 MB
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The prevalence of obesity in the United States and the rest of the industrialized world has skyrocketed in the past 20 years. Linked to heart disease, diabetes, hypertension, and metabolic syndrome, it is also the leading cause of osteoarthritis and the second leading cause of cancer. With contributions from leading experts in the field, Obesity: Prevention and Treatment bridges the gap between emerging understanding of the pathophysiology of obesity with concrete clinical applications for physicians and other healthcare workers in all disciplines of medicine. Following an overview of issues related to the prevention and management of obesity, the book discusses: Energy balance, the metabolic predictors of weight gain, and the role of adipokines, genetics, and the environment on obesity The epidemiology of obesity The identification and evaluation of the overweight patient as a guide to the selection of treatment Nutritional aspects of obesity treatment and management Exercise risks to which the obese patient may be more prone and steps that can be taken to mitigate these risks Behavior modification strategies for the obese patient The definition, assessment, consequences, and treatment of childhood obesity Drugs and surgical options for treatment The implications of public policy on the problem of obesity The significance of intra-abdominal and ectopic fat deposition in endocrine aspects of obesity Currently, over two thirds of the adult population in the United States is either overweight or obese. With these grim statistics, it is critically important that clinicians from all branches of medicine play an active role in diagnosing and treating obesity and its related conditions. This volume arms clinicians with the information they need to create an appropriate prevention and treatment program for their patients.

Pediatric Endocrinology E Book

Author : Mark A. Sperling
File Size : 23.38 MB
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In a single, convenient volume, Pediatric Endocrinology offers complete coverage of all aspects of basic science and clinical practice, ideal for both pediatricians and endocrinologists. Pediatric endocrinology expert Dr. Mark Sperling teams up with world-renowned authors to bring you up to date with the latest key developments in every area of the field, providing invaluable guidance on how your clinical decision making will be affected by today’s technological and scientific advances. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Determine the best possible course for every patient with easy-to-follow algorithms in every clinical chapter. Stay up to date with today’s hottest topics, including neonatal diabetes mellitus, Type II childhood diabetes, molecular endocrinology, and genetics. Explore the impact of today’s advances and challenges, including explosive growth in molecular biology, sophisticated imaging techniques, and an increase in both pediatric diabetes and obesity. Quickly access the information you need with a new, streamlined organization (Concepts, Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests and Imaging).

Clinical Biochemistry E Book

Author : William J. Marshall
File Size : 41.46 MB
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Essential reading for candidates for the MRCPath examination and similar postgraduate examinations in clinical biochemistry. The book gives an overview of the acquisition of data, as well as concentrating on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management. In common with other diagnostic specialties clinical biochemistry now uses an increasing number of techniques involving the 'new biology': these are covered in this book. It is also increasingly common for medically qualified clinical biochemists to become involved in the clinical management of patients (eg nutritional support) and material on this will be included. From the author of the popular Clinical Chemistry medical student textbook. Although there are many competing texts on clinical chemistry, the vast majority concentrate on the technology; this book concentrates on the clinical. Ideally suited for preparation for the MRCPath and similar examination. Significant changes to content to reflect changes in how clinical chemistry services are organised and to reflect the advent of metabolic medicine as a recognised specialty. Chapter on Clinical biochemistry of nutrition to include new information on regulation of appetite and the clinical management of obesity. New chapter to bring together information on inborn errors of metabolism affecting adults. New chapter on clinical biochemistry of cardiovascular disease. The diabetes chapter has been split into two separate chapters to allow more detailed description of the practical clinical management of the disease.

Maternal Obesity

Author : Matthew W. Gillman
File Size : 20.91 MB
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Afflicting more than 300 million women across the globe, obesity has profound effects on health during pregnancy and on the wellbeing of the unborn child. In the face of such a challenging pandemic, this book reviews the latest research and provides up-to-date advice on clinical management. Maternal Obesity addresses the adverse effects of obesity among women of childbearing age, including infertility, medical complications, problems in labor, and adverse birth outcomes, and it reviews evidence that the obese mother's in utero environment has long-lasting influences on the health of the developing child. Chapters cover basic, clinical, and population perspectives, providing a range of valuable information from mechanistic insight through to public health and policy implications. Invaluable for obstetricians, gynaecologists, paediatricians, general and family physicians, subspecialists in obstetric and paediatric medicine, midwives, and dietitians, as well as researchers and public health policy makers seeking to tackle the burden of maternal obesity-related illness.

Bariatric Endoscopy

Author : Christopher C. Thompson
File Size : 38.46 MB
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To date, diet programs and medical therapies for the treatment of obesity have had limited success. Bariatric surgery, however, provides a means of effective weight loss for many of those with morbid obesity. Most of these weight loss procedures are performed with a variety of techniques that continue to evolve. Each technique is associated with unique challenges and complications and it is important for the clinician to be knowledgeable about the endoscopic management of these patients. Additionally, as endoscopic technology evolves it may offer more than just the diagnosis and treatment of complications. Endoscopic therapy may soon allow less invasive bariatric revision procedures as well as a variety of primary obesity therapies for various patient populations. Bariatric Endoscopy reviews the management of obesity, normal post-surgical anatomy, endoscopic and medical management of post-surgical complications, and future endoscopic therapies for obesity management. Organized into five sections, the volume covers an obesity overview, traditional therapy, endoscopy and the bariatric patient, medical management of post-surgical complications, and the future role of endoscopy in obesity management. Detailed illustrations are also provided for surgical procedures, complications and obesity management chapters. Authored by authorities in the field, Bariatric Endoscopy is an indispensible tool for the gastroenterologist or surgical endoscopist as they care for patients with complicated bariatric issues.