Search results for: the-slow-inward-current-and-cardiac-arrhythmias

The Slow Inward Current and Cardiac Arrhythmias

Author : Douglas P. Zipes
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Since Paul Cranefield published his monograph, The Conduction of the Cardiac Impulse, in 1975, much has been learned about the role of the slow inward current in cardiac electrophysiology. Because of this expanse in know ledge, both basic and clinical, it appeared reasonable to review in a mono graph once again what was known. When Martinus Nijhoff first approached us to undertake the task of updating this information, we were initially reluctant for several reasons. First, we did not feel that the subject could be adequately and thoroughly reviewed, from the cell to the bedside, by a single person. Second, time constraints on all of us precluded even attempting such a task. However, we were encouraged by several of our friends (' egged on' one might even say, since they wished the job done but did not want to do it themselves!) who promised faithfully to contribute chapters on time if we accepted the task. So we did, and most of them did also.

Medical Management of Cardiac Arrhythmias

Author : Henri E. Kulbertus
File Size : 79.57 MB
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Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders

Author : Peter H. Stone
File Size : 89.90 MB
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Cardiac Muscle The Regulation Of Excitation And Contraction

Author : Richard Nathan
File Size : 20.3 MB
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Cardiac Muscle: The Regulation of Excitation and Contraction is a 12-chapter text that covers the research studies on characterizing the ionic and molecular mechanisms that regulate excitation and contraction of cardiac muscle. This book describes first the ionic currents underlying diastolic depolarization and pacing of the heart. The discussions then shift to the mechanisms of action of calcium-channel antagonists; the regulation of calcium influx by indigenous factors, such as voltage- or calcium-mediated inactivation; the identification of fixed negative charges on the surface of the sarcolemma; and the regulation of gating and permeability of ion channels by these charges. These topics are followed by examining the molecular and ionic mechanisms that underlie the electrophysiologic actions of adrenergic and cholinergic neurotransmitters and peptide hormones. This text further explores the theoretical and experimental studies of the sodium-calcium exchange process, its stoichiometry, and how the exchanger might contribute to current flow during or after the action potential. Other chapters consider the mechanism of twitch and tonic tension regulation by cardiac glycosides and intracellular sodium and how toxic concentrations induce cardiac arrhythmias. A chapter highlights the identification of sarcolemmal binding sites for calcium, the likelihood that such binding or the release of calcium from the sarcoplasmic reticulum plays a role in the regulation of contraction and the release of calcium from the sarcoplasmic reticulum. The remaining chapters deal with the structural similarities among calcium-binding proteins of the contractile apparatus and the calcium channel, and the regulation of contraction by calcium-binding proteins. Physiologists, pathophysiologists, clinicians, researchers, and students who are interested in heart’s function will find this book invaluable.

Cardiac Arrhythmias

Author : J. Cosin
File Size : 61.43 MB
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Journal of molecular and cell cardiology

Author :
File Size : 89.41 MB
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Control and Manipulation of Calcium Movement

Author : Biological Council. Co-ordinating Committee for Symposia on Drug Action
File Size : 67.41 MB
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Clinical Management of Cardiac Arrhythmias

Author : G. Neal Kay
File Size : 45.24 MB
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A comprehensive discussion of arrhythmia diagnosis and treatment, focusing on the principles, indications, and applications of electrophysiologic techniques in the treatment of specific arrhythmias, Is presented in this excellent text. Topics include programmed electrical stimulation, interventional electrophysiology, temporary and permanent antitachycardia and rate-adaptive pacing techniques, signal averaging, and much more. Patient care and nursing management are integrated throughout the text.

Symposium on Cardiac Arrhythmias II

Author :
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Frontiers of Cardiac Electrophysiology

Author : M.B. Rosenbaum
File Size : 21.59 MB
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The goal of this book is to provide an integrated overview of some intriguing problems of cardiac electrophysiology. Topics have been selected that encompass mainly aspects which have been a matter of concern and interest in our Department over the past few years. We requested from the authors not only that they provide information about their own investiga tions, but also that they integrate their results with those published by oth ers. Furthermore, we urged them to be speculative in their interpretations in order to encourage exploration of related areas of investigation. To this end, the authors have presented their ,contributions in sufficient detail so that the information may not only educate the reader but also encourage and chal lenge him. It is through the concept of total integration -from in vitro to in vivo, from animal to man, from the pure scientist to the clinician -that we hope to advance our understanding of cardiac electrophysiology. The book brings together scientific work in which important advances have been made in the seventies, and in which even more substantial pro gress is likely to be made in the present decade. The chapters have been written by investigators who are authorities in the relevant scientific field. No attempt at summarizing has been made as this may not seldom lead to oversimplification, a risk that we do not dare take. The table of contents and list of contributors are, in this regard, self-explanatory.

Comprehensive Cardiac Care

Author : Marguerite Rodgers Kinney
File Size : 77.89 MB
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European journal of physiology

Author :
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Journal of Cardiovascular Pharmacology

Author :
File Size : 24.29 MB
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Cardiovascular Drugs and the Management of Heart Disease

Author : Gordon A. Ewy
File Size : 73.7 MB
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A revised and updated second edition of this clinical reference text, providing information on the clinical pharmacology, clinical indications, use, and relative costs of all cardiac and cardiovascular drugs available in 1991.

Medicine Science and Society

Author : Kurt J. Isselbacher
File Size : 24.98 MB
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Mathematical Approaches to Cardiac Arrhythmias

Author : José Jalife
File Size : 44.2 MB
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Canadian Journal of Physiology and Pharmacology

Author :
File Size : 90.77 MB
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Philosophical Transactions

Author :
File Size : 43.14 MB
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Basic Neuroscience

Author : Arthur C. Guyton
File Size : 42.63 MB
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Frequency dependent Effects of Verapamil and Nifedipine on the Mechanical Response to Ouabain in Guinea pig Myocardium

Author : Peer Bryngel Jacobson
File Size : 83.42 MB
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